Jennifer R Allen Selected Research

AMG 333

1/2018

Discovery of TRPM8 Antagonist ( S)-6-(((3-Fluoro-4-(trifluoromethoxy)phenyl)(3-fluoropyridin-2-yl)methyl)carbamoyl)nicotinic Acid (AMG 333), a Clinical Candidate for the Treatment of Migraine.

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Jennifer R Allen Research Topics

Disease

5	Neoplasms (Cancer) 01/2022 - 09/2004
3	Alzheimer Disease (Alzheimer's Disease) 12/2020 - 12/2013
2	Hypoxia (Hypoxemia) 09/2010 - 09/2008
1	Migraine Disorders (Migraine) 01/2018
1	Anemia 01/2017
1	Neurobehavioral Manifestations 10/2015
1	Schizophrenia (Dementia Praecox) 02/2015
1	Huntington Disease (Huntington's Disease) 02/2015
1	Nervous System Diseases (Neurological Disorders) 02/2015
1	Hyperalgesia 01/2012
1	Chronic Pain 01/2012
1	Pain (Aches) 10/2011
1	Edema (Dropsy) 10/2011
1	Inflammation (Inflammations) 10/2011
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 09/2004

Drug/Important Bio-Agent (IBA)

1	KinesinsIBA 01/2022
1	EnzymesIBA 12/2020
1	Proteins (Proteins, Gene)FDA Link 12/2020
1	Aspartic Acid ProteasesIBA 12/2020
1	Amyloid (Amyloid Fibrils)IBA 12/2020
1	sotorasibIBA 01/2020
1	CationsIBA 01/2018
1	AcidsIBA 01/2018
1	AMG 333IBA 01/2018
1	HepcidinsIBA 01/2017
1	IronIBA 01/2017
1	metal transporting protein 1 (ferroportin)IBA 01/2017
1	Cholinergic Agents (Cholinergics)IBA 10/2015
1	Muscarinic M1 ReceptorIBA 10/2015
1	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 02/2015
1	Phosphotransferases (Kinase)IBA 01/2015
1	LigandsIBA 01/2015
1	AmidesIBA 12/2013
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 12/2013
1	O-(glucuronic acid 2- sulfate)- (1- - 4)- O- (2,5)- anhydromannitol 6-sulfateIBA 12/2013
1	CarrageenanIBA 01/2012
1	5-chlorochromenoneIBA 01/2012
1	Bradykinin B1 ReceptorIBA 10/2011
1	Transcription Factors (Transcription Factor)IBA 09/2010
1	Prolyl Hydroxylases (Prolyl Hydroxylase)IBA 09/2010
1	QuinolonesIBA 09/2010
1	BenzimidazolesIBA 09/2008
1	keyhole-limpet hemocyanin (keyhole limpet hemocyanin)IBA 09/2004
1	Surface Antigens (Surface Antigen)IBA 09/2004
1	fucosyl GM1 gangliosideIBA 09/2004
1	Complement System Proteins (Complement)IBA 09/2004
1	Immunoglobulin M (IgM)IBA 09/2004

Therapy/Procedure

1	Immunotherapy 09/2004